I haven't used MD for some years now, but there was a tutorial over on their website on how to set up anchor points and bounding volumes for one of the Genesis figures. I did go through it and it did set up the bounding volumes correctly but it was so much finicky and lengthy work that I didn't bother for my second avatar import. You can create clothing just fine without bounding volumes, you just need to place the pattern manually in the 3D window before running a simulation.