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The human kidney is a paired bean-shaped organ that purifies the blood and regulates the body's chemical homeostasis through the function of urine formation. It is a multi-lobed, multi-papillary kidney of a mammal, usually without external signs of lobulation. It is part of the urinary system (urinary system). They are located in the lumbar region, retroperitoneally, on both sides of the spine, and are comparable in size to a human fist.

The kidneys are vital organs of the body. If they are seriously damaged, many diseases associated with them are incurable. Therefore, they are an important object of medical research and preclinical studies of drugs.