Dragon Quest X features user-created characters with the series' traditional job system, with Warrior, Priest, Mage, Martial Artist, Thief, and Minstrel as starter jobs. Unlike previous games, jobs can be changed in any of the game's towns.[2]

Dragon Quest X is the first numbered title that breaks the Dragon Quest tradition of turn-based combat; the combat becomes more action-based by breaking the order of the attacks.

The game includes a quest system similar to that of Dragon Quest IX. Quests serve as side-stories helping non-player characters around the game's world. Multiple quests can be performed simultaneously with some even interlocking and unlocking various stages in fellow quests. Early quests include gathering magical spring water, slaying monsters and stealing for a fellow thief. Like the previous Dragon Quest installment, Dragon Quest X contains many open ended mini-quests. Upon completion of the quests, a Quest List log, serving as an in-game achievement list. There are also brand new Job quests that can only be received when the player is practicing specific jobs.